Tag Archives: Kill cancer

Modulight Spotlights: LASER-SHARP RESEARCH – July 2021

 Modulight Spotlights: LASER-SHARP RESEARCH – July 2021 Congratulations for Gina Manda and her team at Victor Babes National Institute of Pathology! Their genetic study unveiled a network of stress responses in tumor cells triggered by PDT. These results expand knowledge of different mechanisms behind therapy-induced cell death and treatment resistance. Read original publication   Modulight is very happy to be supporting this research. We would like to deliver our warmest congratulations to the research team!   #LaserSharpResearch  #ModulightInScience   #LasersInScience #KillCancer  #ColonCancer #Genetics     Continue reading →

Modulight Spotlights: LASER-SHARP RESEARCH – June 2021

Modulight Spotlights: LASER-SHARP RESEARCH – June 2021 The findings by Prof. Lothar Lilge and his team might enable improved treatment of diffuse lung metastasis which are difficult to treat with standard therapies. A novel lung perfusion platform significantly reduced tissue absorption and allowed better light penetration, resulting in up to 3-fold increased treatment volumes.   Read original publication   Modulight is very happy to be supporting this research. We would like to deliver our warmest congratulations to the research team!   #LaserSharpResearch  #ModulightInScience   #LasersInScience Continue reading →

ML7710 for photoimmunotherapy against regulatory T cells in tumors

    Results Tumor growth was significantly suppressed by photoimmunotherapy, compared to control or IgG without light activation. Tumor growth suppression, as well as overall survival after photoimmunotherapy, were significantly better with F(ab´)2 fragments than with full IgG. This efficacy improvement might be related to killer T cells, which were detected in much higher numbers after photoimmunotherapy with F(ab´)2 fragments and are key cells for the generation of efficient systemic antitumor immunity.       Related Modulight products and Services   Related Publications The Effect Continue reading →Customer case The Laboratory of Molecular Theranostics is a major research section of the Molecular Imaging Program at National Cancer Institute (NCI) and is led by Dr. Hisataka Kobayashi. The groundbreaking research includes the development of imaging and theranostic probes, which can aid in cancer detection and treatment. Dr. Kobayashi has invented near-infrared photoimmunotherapy (NIR-PIT) with IRDye700DX, which is currently in FDA-designated fast-track Phase 3 trials for inoperable Head & Neck cancer. Dr. Hisataka Kobayashi M.D., PhD   Dr. Peter L. Choyke M.D., PhD   Continue reading →

Modulight Spotlights: LASER-SHARP RESEARCH – May 2021

Modulight Spotlights: LASER-SHARP RESEARCH – May 2021 The renowned pioneer in photoimmunotherapy (PIT), Professor Hisataka Kobayashi, has published an outstanding article with his team at National Cancer Institute / NIH. The article is about improving the antitumor efficacy of near-infrared photoimmunotherapy (NIR-PIT) by simultaneous targeting of cancer cells and regulatory T cells in the tumor microenvironment. Read original publication   Modulight is very happy to be supporting this research. We would like to deliver our warmest congratulations to the research team!   #LaserSharpResearch  #ModulightInScience   Continue reading →

Modulight Spotlights: LASER-SHARP RESEARCH – April 2021

Modulight Spotlights: LASER-SHARP RESEARCH – April 2021 Dr. Rhonda Kines and the team at Aura Biosciences reported promising results of their VLP (virus-like particle) photosensitizer-conjugate eliciting strong and long-lasting anti-tumor immune responses, as well as potential to combine this agent with immune checkpoint inhibitors for even improved antitumor efficacy. Read original publication   Modulight is very happy to be supporting this research. We would like to deliver our warmest congratulations to the research team!   #LaserSharpResearch #ModulightInScience   #LasersInScience #KillCancer #UvealMelanoma   Modulight products used: Continue reading →