Tag Archives: Kill cancer

ML7710 for photoimmunotherapy against regulatory T cells in tumors

      Experiments Tumor-bearing mice were randomized into 4 groups: 1) no treatment (control), 2) anti-CD25 full IgG antibody (no light activation), 3) anti-CD25 F(ab’)2 fragment, and 4) anti-CD25 full IgG antibody. NIR light using ML7710 (689 nm, 150 mW/cm2, 50 J/cm2) was administered to group 3 and 4 mice on day 1 (PIT). Tumor volumes were monitored for 21 days and survival of mice for up to 80… READ MORE